Steady Heart. Steady Numbers.
Built for consistent daily use, so your heart microbiome, energy, and cardiovascular function keep getting steadier over time.
Most Popular Searches
Free Shipping
365-Day Money-Back Guarantee
† Testimonials within our advertisement are real life reactions of real customers at Simple Promise™; however their names have been changed for privacy. Individual results may vary.
Please Note: The material on this site is provided for informational purposes only and is not medical advice. Always consult your physician before beginning any diet or exercise program.
Combine with our other products for a health boost.
Gut-to-Heart Probiotic Support
Stimulant & Caffeine-Free
Gluten-Free
Sugar Free
Non-GMO
Vegetarian-Friendly
of participants in a clinical trial showed measurable drops in ApoB48, the protein that carries cholesterol into the arteries
reduction in TMAO levels versus baseline after 28 days of the KABP® probiotic blend
reduction in heart failure mortality in a randomized study of 420 patients supplementing with CoQ10
Cardiovascular Research (Oxford Academic), 2024 ² Q-SYMBIO study, reviewed in Frontiers in Nutrition, 2025
The KABP® Cardio Blend delivers three probiotic strains studied in human research for cardiovascular markers.¹
TMAO is a compound linked to cardiovascular risk. In a clinical study, KABP® strains supported a 2-to-4-fold reduction in TMAO over 28 days.²
Artichoke extract supports your liver's natural cholesterol-clearance pathway through bile production. ³
Bioactive CoQ10 and standardized artichoke extract have been studied for blood pressure support already in the normal range. ⁴ ⁵
Your heart cells run on mitochondria, and mitochondria run on CoQ10. Bioavailable CoQ10 fuels the cells that never stop working. ⁶
Three clinically studied strains derived from traditional fermented plant beverages, vegetarian, non-GMO.
Most probiotics on the market are designed for digestion. They live in your gut, do their job, and that's where the story ends. The CardioBiome™ blend was developed for something completely different, supporting the microbiome of the heart itself.
Researchers at one of Japan's leading biotech institutions identified a family of probiotic bacteria called Lactiplantibacillus — "lacti" meaning milk-based fermentation, "plantarum" meaning plant-origin. From this family, three specific strains were isolated and clinically studied for cardiovascular support:
The first of three Lactiplantibacillus plantarum strains studied in a 28-day human trial for cardiovascular markers.⁷
Works in synergy with KABP®011 and KABP®013 as part of the patented Cardio Blend.⁸
Completes the trio. In the clinical trial, the three strains together supported a 2-to-4-fold TMAO reduction.⁹
CardioBiome™ uses a highly bioavailable form clinically studied for cardiovascular support. In a randomized study of 420 patients with severe heart failure tracked for two years, CoQ10 supplementation was associated with a significant reduction in mortality compared to placebo. ¹⁰ ¹¹ Additional research has shown CoQ10 may support healthy blood pressure already in the normal range. ¹²
Artichoke leaf extract — standardized to the active compound cynarin — has been studied for its support of healthy cholesterol metabolism through bile flow. ¹³ A randomized trial of 107 adults with elevated blood pressure who supplemented with artichoke extract for 12 weeks showed statistically significant reductions in both systolic and diastolic readings versus placebo.¹⁴
|
|
|
|
|---|---|---|---|
| Criteria | CardioBiome™ | Standard Probiotics | Generic CoQ10 |
| Targets Gut-Heart Connection | |||
| Clinically Studied For TMAO Support | |||
| Includes 3 Specific KABP® Strains | |||
| Bioavailable CoQ10 Form | Varies | ||
| Standardized 2.5% Cynarin Artichoke | |||
| Acid-Resistant Delivery | Varies | ||
| cGMP-Certified Manufacturing | Varies | Varies | |
| 365-Day Guarantee |
We are confident in every one of our supplements. If at any time during those 365 days you aren’t 100% satisfied with your order, simply return it for a full and immediate refund. No questions asked.
1 https://academic.oup.com/cardiovascres/article/120/7/708/7634448
2 Ibid. The 28-day clinical trial showed TMAO levels reduced 2-to-4-fold versus baseline.
3 https://pmc.ncbi.nlm.nih.gov/articles/PMC6271736/
4 https://pmc.ncbi.nlm.nih.gov/articles/PMC8066821/
5 https://pmc.ncbi.nlm.nih.gov/articles/PMC10974306/
6 https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1504831/full
7 https://academic.oup.com/cardiovascres/article/120/7/708/7634448
8 https://academic.oup.com/cardiovascres/article/120/7/708/7634448
9 https://academic.oup.com/cardiovascres/article/120/7/708/7634448
10 https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1504831/full
11 https://pmc.ncbi.nlm.nih.gov/articles/PMC8066821/
12 https://pmc.ncbi.nlm.nih.gov/articles/PMC8066821/
13 https://pmc.ncbi.nlm.nih.gov/articles/PMC6271736/
14 https://pmc.ncbi.nlm.nih.gov/articles/PMC10974306/
15 https://academic.oup.com/cardiovascres/article/120/7/708/7634448
